R53.81
BillableOther malaise
R53.81 is the ICD-10-CM code for Other malaise. It is a billable, specific code valid for reimbursement.
R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
What this means — in plain language
MedlinePlus · NIHWhat is fatigue? Fatigue is a feeling of weariness, tiredness, or lack of energy. It can interfere with your usual daily activities. Fatigue can be a normal response to physical activity, emotional stress , boredom, or lack of sleep. But sometimes it can be a sign of a mental or physical condition. If you have been feeling tired for weeks, contact your health care provider. They can help you find out what's causing…
Read more about Fatigue at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Includes
- •Chronic debility
- •Debility NOS
- •General physical deterioration
- •Malaise NOS
- •Nervous debility
Excludes1 — not coded here
- •age-related physical debility (R54)
Medications indicated for this condition
FDA labeling- Allium Sat, Anacardium, Apis Mel, Gambogia, Merc Solub, Nat Carb, Nitricum Ac, Nux Vom, Phosphorus, Pulsatilla, SulphurStandardized Insect Venom Allergenic Extract [EPC]›
- Apil Mel, Baptisia, Baryta Carb, Hamamelis, Kali Brom, Kali Phos, Lachesis, Lilium, Petroleum, Phosphoricum Ac, Spigelia Anth, Sulphur, Veratrum VirStandardized Insect Venom Allergenic Extract [EPC]›
Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Conditions mapped to this code
MedlinePlus · NIHPlain-language health-topic references grounded in MedlinePlus (NIH/NLM).
Frequently asked questions
- What is ICD-10 code R53.81?
- R53.81 is the ICD-10-CM code for "Other malaise". It falls under R00-R99 Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified.
- Is R53.81 a billable code?
- Yes — R53.81 is a billable, specific ICD-10-CM code valid for reimbursement.
- What is excluded from R53.81?
- Excludes1 (not coded here): age-related physical debility (R54).
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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