E34.321
BillablePrimary insulin-like growth factor-1 (IGF-1) deficiency
E34.321 is the ICD-10-CM code for Primary insulin-like growth factor-1 (IGF-1) deficiency. It is a billable, specific code valid for reimbursement.
E00-E89 Endocrine, nutritional and metabolic diseases
What this means — in plain language
MedlinePlus · NIHDoes your child seem much shorter - or much taller - than other kids his or her age? It could be normal. Some children may be small for their age but still be developing normally. Some children are short or tall because their parents are. But some children have growth disorders. Growth disorders are problems that prevent children from developing normal height, weight, sexual maturity or other features. Very slow or…
Read more about Growth Disorders at MedlinePlus ↗Source: U.S. National Library of Medicine (MedlinePlus). Informational only — not medical advice.
Includes
- •Acid-labile subunit gene (IGFALS) defect
- •Growth hormone gene 1 (GH1) defect with growth hormone neutralizing antibodies
- •Growth hormone insensitivity syndrome (GHIS)
- •Insulin-like growth factor 1 gene (IGF1) defect
- •Laron type short stature
- •Severe primary insulin-like growth factor-1 deficiency (SPIGFD)
- •Signal transducer and activator of transcription 5B gene (STAT5b) defect
Medications indicated for this condition
FDA labeling- TestosteroneAndrogen [EPC]›
- SomatropinRecombinant Human Growth Hormone [EPC]›
- Fludrocortisone›
- Arginine›
- LonapegsomatropinRecombinant Human Growth Hormone [EPC]›
- MacimorelinGrowth Hormone Secretagogue Receptor Agonist [EPC]›
- Triamcinolone Acetonide, Lidocaine Hydrochloride, Bupivacaine Hydrochloride, Povidine Iodine›
Drugs whose FDA labeling lists this condition's category among its indications. Informational only — not a treatment recommendation or medical advice.
Conditions mapped to this code
MedlinePlus · NIHPlain-language health-topic references grounded in MedlinePlus (NIH/NLM).
Frequently asked questions
Source: CMS ICD-10-CM FY2026. For informational purposes only — not medical advice. See our medical disclaimer.
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